Joachim graduated from University of Copenhagen (Denmark) in 2017 with both Bachelor of Sciences and Cand. Scient. degrees in Biology-Biotechnology with specialization in Applied Enzymology. He initially studied alkaloid biosynthesis in plants, then later specialised in glycosylation pathways from plants, yeast and humans.
In 2018, he relocated to University of Newcastle (UoN), focusing on polyketide synthesis and their biological function in cyanobacteria (‘blue-green algae’). Deciphering the potential of cyanobacteria to produce polyketides are of importance due to their antimicrobial and immunosuppressive properties. However, the potential of polyketide production in cyanobacteria has been understudied. Therefore, heterologous expression of genes encoding polyketide synthases are carried out in different host organisms to study their product formation and the biosynthesis of these polyketides.
Combining the heterologous expression with knockout studies in the native organisms will help decipher the function of these metabolites. Looking at the difference on the proteomics and metabolomics levels between the knockouts and the WT cells can help elucidate the biological function these polyketides have in their native organisms.
Outside the phd work, Joachim is on the advisory team for the iGEM 2020 team from Newcastle. Otherwise, he enjoys hiking, reading, and playing video games.