Postdoctoral Research Associate
Location: Neilan Laboratory of Microbial and Molecular Diversity
School of Environmental and Life Sciences
University of Newcastle, Callaghan, NSW, Australia
Available for immediate start
Academic Level: A
Contract type: Full time. Fixed term, 1 year with opportunity for extension
About the role: An exciting opportunity to develop and undertake cutting edge research and provide research support within the Neilan Laboratory of Microbial and Molecular Diversity. Applications are invited for a postdoctoral research associate to lead the heterologous expression of enzymes involved in the biosynthesis of cyanobacterial toxins and other bioactive molecules.
Under the direction of Prof. Neilan, the successful applicant will independently carry out research activities and work collaboratively with members of the research group, supervise research students, prepare manuscripts and assist with other forms of scientific writing.
Applicants must have experience in molecular biology and possess a doctoral degree (or shortly satisfy the requirements of a PhD) in a relevant scientific discipline. A strong publication record, relative to opportunity is desired. Additionally, the applicant must possess excellent written and oral communication skills and the ability to priorities tasks to meet deadlines.
Competency in the following techniques is desired:
– Genome mining
– Large insert clone library construction/fosmid cloning
– Cloning and expression of genes /gene clusters in heterologous hosts
– Enzyme purification and biochemical analyses
– Extraction, purification and structural characterisation of natural products
– Analytical chemistry
About the institute: The University of Newcastle (UON) stands as a global leader, distinguished by a commitment to equity and excellence, and to creating a better future for its regions through a focus on innovation and impact. Located on the east coast of Australia (1.5 hours north of Sydney), Newcastle is situated in the heart of the Hunter Region and is bordered by a stunning coastline with beautiful beaches.
How to apply: Applications should be emailed to the laboratory manager:
Format: Please send a single document, including a cover letter outlining your motivations, a response to the selection criteria and your CV.
Higher Research Degree Opportunities
These PhD opportunity does not guarantee a scholarship.
To also be considered for a scholarship please submit an application in the relevant scholarship round.
Genetic and Environmental Drivers of Neurotoxic Cyanobacterial Blooms
Australian freshwater systems are plagued by toxic cyanobacterial (“blue-green algal”) blooms. Mitigating the effects of these blooms is a major challenge in protecting the nation’s water supplies. We will apply a state-of-the-art, genetic and biochemical approach to identify the mechanisms of adaptation used by the bloom-forming and neurotoxic cyanobacterial genera Anabaena and Dolichospermum. This project will, for the first time, assess their capacity for increased dominance, intensity and geographical distribution in Australian waterways. Understanding the molecular ecophysiology of these aquatic microorganisms is essential for improving risk assessment protocols and reducing the impact of harmful blooms.
Ramifications of Climate Change on Microbial Ecology in the Pacific Ocean
Microbial biodiversity in the tidal zone is responsible for important biological processes such as geochemical cycling and carbon sequestration. Climate change in the Pacific Islands has resulted in the restructuring of these zones effecting local freshwater ecology.
The tidal interface between the ocean and land is a complex microbiome and increased rates of shoreline recession and an increased incidence of extreme meteorological events, a consequence of climate change has resulted in a changing biological diversity. The research project will endeavour to monitor the effects of climate change through assembling locally relevant biodiversity markers for the Pacific Islands and through using Next Generation Technologies will assess the changing microbial profiles at the tidal interface. Research will heavily focus on cyanobacteria and its role in nutrient cycling in the Pacific Ocean. It will also include investigation into the microbial biodiversity and metabolomic profiles of different atolls to survey the ecological influence of niche environments on local community structures. Possible outcomes for this project include the development of a predictive model to assess the effects of global warming on biodiversity.
Interested applicants should send an email expressing their interest along with scanned copies of their academic transcripts, CV, a brief statement of their research interests and a proposal that specifically links them to the research project.
Please send the email expressing interest to Toby.Mills@newcastle.edu.au